A pilot study to compare two types of heat-stabilized rice bran in modifying compositions of intestinal microbiota among healthy Chinese adults
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Muthayya S, Sugimoto JD, Montgomery S, Maberly GF. An overview of global rice production, supply, trade, and consumption. Ann N Y Acad Sci 2014; 1324: 7–14. doi: 10.1111/nyas.12540.
Sharif MK, Butt MS, Anjum FM, Khan SH. Rice bran: A novel functional ingredient. Crit Rev Food Sci Nutr 2014; 54(6): 807–816. doi: 10.1080/10408398.2011.608586.
Fabian C, Ju YH. A review on rice bran protein: Its properties and extraction methods. Crit Rev Food Sci Nutr 2011; 51(9): 816–827. doi: 10.1080/10408398.2010.482678.
Henderson AJ, Ollila CA, Kumar A, Borresen EC, Raina K, et al. Chemopreventive properties of dietary rice bran: Current status and future prospects. Adv Nutr 2012; 3(5): 643–653. doi: 10.3945/an.112.002303.
Wang O, Liu J, Cheng Q, Guo X, Wang Y, et al. Effects of ferulic acid and γ-oryzanol on high-fat and high-fructose diet induced metabolic syndrome in rats. PLoS One 2015; 10(2): e0118135. doi: 10.1371/journal.pone.0118135.
Srinivasan M, Sudheer AR, Menon VP. Ferulic Acid: Therapeutic potential through its antioxidant property. J Clin Biochem Nutr 2007; 40(2): 92–100. doi: 10.3164/jcbn.40.92.
Sivagami G, Karthikkumar V, Balasubramanian T, Nalini N. The modulatory influence of p-methoxycinnamic acid, an active rice bran phenolic acid, against 1, 2-dimethylhydrazine-induced lipid peroxidation, antioxidant status and aberrant crypt foci in rat colon carcinogenesis. Chem Biol Interact 2012; 196(1–2): 11–22. doi: 10.1016/j.cbi.2012.01.008.
Shibata A, Nakagawa K, Sookwong P, Tsuduki T, Tomita S, et al. Tocotrienol inhibits secretion of angiogenic factors from human colorectal adenocarcinoma cells by suppressing hypoxia-inducible factor-1alpha. J Nutr 2008; 138(11): 2136–2142. doi: 10.3945/jn.108.093237.
Shafie NH, Esa NM, Ithnin H, Saad N, Pandurangan AK. Pro-apoptotic effect of rice bran inositol hexaphosphate (IP6) on HT-29 colorectal cancer cells. Int J Mol Sci 2013; 14(12): 23545–23558. doi: 10.3390/ijms141223545.
Al-Fatlawi AA, Al-Fatlawi AA, Irshad M, Zafaryab M, Rizvi MM, Ahmad A. Rice bran phytic acid induced apoptosis through regulation of Bcl-2/Bax and p53 genes in HepG2 human hepatocellular carcinoma cells. Asian Pac J Cancer Prev 2014; 15(8): 3731–3736.
Minhajuddin M, Beg ZH, Iqbal J. Hypolipidemic and antioxidant properties of tocotrienol rich fraction isolated from rice bran oil in experimentally induced hyperlipidemic rats. Food Chem Toxicol 2005; 43(5): 747–753.
Justo ML, Claro C, Zeyda M, Stulnig TM, Herrera MD, et al. Rice bran prevents high-fat diet-induced inflammation and macrophage content in adipose tissue. Eur J Nutr 2016; 55(6): 2011–2019. doi: 10.1007/s00394-015-1015-x.
Ley RE, Bäckhed F, Turnbaugh P, Lozupone CA, Knight RD, et al. Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A 2005; 102(31): 11070–11075.
Marchesi JR, Dutilh BE, Hall N, Peters WH, Roelofs R, et al. Towards the human colorectal cancer microbiome. PLoS One 2011; 6(5): e20447. doi: 10.1371/journal.pone.0020447.
Chen W, Liu F, Ling Z, Tong X, Xiang C. Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer. PLoS One 2012; 7(6): e39743. doi: 10.1371/journal.pone.0039743.
Zhu Q, Jin Z, Wu W, Gao R, Guo B, et al. Analysis of the intestinal lumen microbiota in an animal model of colorectal cancer. PLoS One 2014; 9(6): e90849. doi: 10.1371/journal.pone.0090849.
Castellarin M, Warren RL, Freeman JD, Dreolini L, Krzywinski M, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res 2012; 22(2): 299–306. doi: 10.1101/gr.126516.111.
Gao Z, Guo B, Gao R, Zhu Q, Qin H. Microbiota disbiosis is associated with colorectal cancer. Front Microbiol 2015; 6: 20. doi: 10.3389/fmicb.2015.00020.
Rubinstein MR, Wang X, Liu W, Hao Y, Cai G, et al. Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin. Cell Host Microbe 2013; 14(2): 195–206. doi: 10.1016/j.chom.2013.07.012.
Mira-Pascual L, Cabrera-Rubio R, Ocon S, Costales P, Parra A, et al. Microbial mucosal colonic shifts associated with the development of colorectal cancer reveal the presence of different bacterial and archaeal biomarkers. J Gastroenterol 2015; 50(2): 167–179. doi: 10.1007/s00535-014-0963-x.
Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 2007; 104(34): 13780–13785.
Morgan XC, Tickle TL, Sokol H, Gevers D, Devaney KL, et al. Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment. Genome Biol 2012; 13(9): R79. doi: 10.1186/gb-2012-13-9-r79.
Brestoff JR, Artis D. Commensal bacteria at the interface of host metabolism and the immune system. Nat Immunol 2013; 14(7): 676–684. doi: 10.1038/ni.2640.
Henderson AJ, Kumar A, Barnett B, Dow SW, Ryan EP. Consumption of rice bran increases mucosal immunoglobulin A concentrations and numbers of intestinal Lactobacillus spp. J Med Food 2012; 15(5): 469–475. doi: 10.1089/jmf.2011.0213.
Kumar A, Henderson A, Forster GM, Goodyear AW, Weir TL, et al. Dietary rice bran promotes resistance to Salmonella enterica serovar Typhimurium colonization in mice. BMC Microbiol 2012; 12: 71. doi: 10.1186/1471-2180-12-71.
Yang X, Twitchell E, Li G, Wen K, Weiss M, et al. High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity. Sci Rep 2015; 5: 15004. doi: 10.1038/srep15004.
Komiyama Y, Andoh A, Fujiwara D, Ohmae H, Araki Y, et al. New prebiotics from rice bran ameliorate inflammation in murine colitis models through the modulation of intestinal homeostasis and the mucosal immune system. Scand J Gastroenterol 2011; 46(1): 40–52. doi: 10.3109/00365521.2010.513062.
Sheflin AM, Borresen EC, Wdowik MJ, Rao S, Brown RJ, et al. Pilot dietary intervention with heat-stabilized rice bran modulates stool microbiota and metabolites in healthy adults. Nutrients 2015; 7(2): 1282–1300. doi: 10.3390/nu7021282.
Chong CW, Ahmad AF, Lim YA, Teh CS, Yap IK, et al. Effect of ethnicity and socioeconomic variation to the gut microbiota composition among pre-adolescent in Malaysia. Sci Rep 2015; 5: 13338. doi: 10.1038/srep13338.
Statistics on behavioural risk factors [Internet] Hong Kong: Centre for Health Protection; 2014 [cited 2017 Nov 6].
Yang B, Wang Y, Qian PY. Sensitivity and correlation of hypervariable regions in 16S rRNA genes in phylogenetic analysis. BMC Bioinformatics 2016; 17: 135. doi: 10.1186/s12859-016-0992-y.
Schloss PD, Westcott SL, Ryabin T, Hall JR, Hartmann M, et al. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl Environ Microbiol 2009; 75(23): 7537–7541. doi: 10.1128/AEM.01541-09.
Trompette A, Gollwitzer ES, Yadava K, Sichelstiel AK, Sprenger N, et al. Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis. Nat Med 2014; 20(2): 159–166. doi: 10.1038/nm.3444.
Den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ, et al. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res 2013; 54(9): 2325–2340. doi: 10.1194/jlr.R036012.
Shoaie S, Karlsson F, Mardinoglu A, Nookaew I, Bordel S, et al. Understanding the interactions between bacteria in the human gut through metabolic modeling. Sci Rep 2013; 3: 2532. doi: 10.1038/srep02532.
Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: Human gut microbes associated with obesity. Nature 2006; 444(7122): 1022–1023.
Voreades N, Kozil A, Weir TL. Diet and the development of the human intestinal microbiome. Front Microbiol 2014; 5: 494. doi: 10.3389/fmicb.2014.00494.
Sheflin AM, Borresen EC, Kirkwood JS, Boot CM, Whitney AK, et al. Dietary Supplementation with Rice Bran or Navy Bean Alters Gut Bacterial Metabolism in Colorectal Cancer Survivors. Mol Nutr Food Res 2016; 61(1). doi: 10.1002/mnfr.201500905.
De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 2010; 107(33): 14691–14696. doi: 10.1073/pnas.1005963107.
Kallus SJ, Brandt LJ. The intestinal microbiota and obesity. J Clin Gastroenterol 2012; 46(1): 16–24. doi: 10.1097/MCG.0b013e31823711fd.
Abdallah Ismail N, Ragab SH, Abd Elbaky A, Shoeib AR, Alhosary Y, et al. Frequency of Firmicutes and Bacteroidetes in gut microbiota in obese and normal weight Egyptian children and adults. Arch Med Sci 2011; 7(3): 501–507. doi: 10.5114/aoms.2011.23418.
Lin HV, Frassetto A, Kowalik EJ Jr, Nawrocki AR, Lu MM, et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PLoS One 2012; 7(4): e35240. doi: 10.1371/journal.pone.0035240.
Chakraborti CK. New-found link between microbiota and obesity. World J Gastrointest Pathophysiol 2015; 6(4): 110–119. doi: 10.4291/wjgp.v6.i4.110.
Hijova E, Chmelarova A. Short chain fatty acids and colonic health. Bratisl Lek Listy 2007; 108(8): 354–358.
Sanz Y, Santacruz A, Gauffin P. Gut microbiota in obesity and metabolic disorders. Proc Nutr Soc 2010; 69(3): 434–441. doi: 10.1017/S0029665110001813.
Psichas A, Sleeth ML, Murphy KG, Brooks L, Bewick GA, et al. The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents. Int J Obes (Lond) 2015; 39(3): 424–429. doi: 10.1038/ijo.2014.153.
Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T, et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 2004; 101(4): 1045–1050.
Song H, Yoo Y, Hwang J, Na YC, Kim HS. Faecalibacterium prausnitzii subspecies-level dysbiosis in the human gut microbiome underlying atopic dermatitis. J Allergy Clin Immunol 2016; 137(3): 852–860. doi: 10.1016/j.jaci.2015.08.021.
Miquel S, Martín R, Rossi O, Bermúdez-Humarán LG, Chatel JM, et al. Faecalibacterium prausnitzii and human intestinal health. Curr Opin Microbiol 2013; 16(3): 255–261. doi: 10.1016/j.mib.2013.06.003.
Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: Links with metabolic and low-grade inflammation markers. Diabetes 2010; 59(12): 3049–3057. doi: 10.2337/db10-0253.
Bibbò S, Ianiro G, Giorgio V, Scaldaferri F, Masucci L, et al. The role of diet on gut microbiota composition. Eur Rev Med Pharmacol Sci 2016; 20(22): 4742–4749.
Monda V, Villano I, Messina A, Valenzano A, Esposito T, et al. Exercise Modifies the Gut Microbiota with Positive Health Effects. Oxid Med Cell Longev 2017; 2017: 3831972. doi: 10.1155/2017/3831972.
DOI: http://dx.doi.org/10.18282/amor.v4.i1.253
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